Tag Archives: antibiotics

The impact of the John Innes Centre

The impact of the John Innes Centre

Every pound invested in John Innes Centre science today will give £12 back to the UK economy in 10 years’ time. That’s the conclusion of an independent report which looks into the impact of the world-leading research at the plant science and microbiology institute on the Norwich Research Park. The report, compiled by Brookdale Consulting, [...]

Read more

Ants and antibiotics

Ants and antibiotics

Norwich scientists are investigating sources of antibiotics which may sound surprising – including ants, stick insects, soil and potatoes. These and other aspects of antibiotic research carried out at the John Innes Centre and the University of East Anglia will feature in the first episode of the BBC’s latest current affairs series Inside Out. Many [...]

Read more

New way to improve antibiotic production

An antibiotic has been found to stimulate its own production. The findings, to be published in PNAS, could make it easier to scale up antibiotic production for commercialisation.   Scientists Dr Emma Sherwood and Professor Mervyn Bibb from the John Innes Centre were able to use their discovery of how the antibiotic is naturally produced [...]

Read more

Q&A with Professor Mervyn Bibb

Q&A with Professor Mervyn Bibb

  The enthusiasm of a school biology teacher helped fuel Professor Mervyn Bibb’s own curiosity. Today, as antibiotic resistance nears a crisis point, his work to understand how soil bacteria produce antibiotics is more vital than ever. What sparked your interest in science? I have always been interested in the “natural world”, but it was [...]

Read more

Molecular microbiology department recruits new project leader

JIC’s molecular microbiology department has recruited a new project leader. Dr Barrie Wilkinson joins JIC from Cambridge drug discovery company Biotica, where he was vice president for research. The importance of the department’s research was highlighted recently when the UK chief medical officer Professor Sally Davies warned of the ‘catastrophic threat” of antimicrobial resistance. She [...]

Read more

Medicinal toothbrush tree yields antibiotic to treat TB in new way

A compound from the South African toothbrush tree inactivates a drug target for tuberculosis in a previously unseen way. Tuberculosis causes more deaths worldwide than any other infectious disease. At the same time as rates are increasing, resistance strains are emerging due, in part, to non-compliance with the treatment required. Current drugs are nearly 50 [...]

Read more

Study looks to separate side effects from antibiotic activity

A new project is investigating whether altering the production of an antibiotic will remove side effects preventing it being used clinically to battle drug-resistant superbugs. Tunicamycin is an antibiotic produced by the soil bacterium Streptomyces that was discovered 40 years ago. It works by blocking cell wall production in bacteria in a clinically novel way, [...]

Read more

Novel method for increasing antibiotic yields

Novel method for increasing antibiotic yields

A novel way of increasing the amounts of antibiotics produced by bacteria has been discovered that could markedly improve the yields of these important compounds in commercial production. It could also be valuable in helping to discover new compounds. With the ever-growing threat from antibiotic resistance, these tools will be very useful in ensuring that [...]

Read more